Science DNA breaks are toxic lesions for the cell. In order to repair these breaks, it is necessary, starting from the break ends, to find a homologous sequence within the vastness of the genome. In ...

The research team has now succeeded in using the CRISPR system to insert the missing letters in the right place. They ...

Unlike cars, a cell has multiple DNA polymerase motors ... whether the enzymatic period was during exonuclease repair or DNA extension. “This experiment is really the nail in the coffin of this model ...

A new species of tardigrades with thousands of genes that become more active when exposed to radiation could help in devising ...

Scientists have discovered a way to target elusive circular fragments of DNA that drive the survival of some of the most aggressive cancers, paving the way for future treatments.

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science ...

These were cells known to be deficient in their ability to repair mismatched DNA sequences generated by mutations and those that bore mutations to a component of their DNA replication machinery, DNA ...

A novel discovery in the field of pancreatic cancer treatment has been unveiled, revealing the epigenetic silencing of BEND4 as a potential synthetic lethal marker for enhancing the efficacy of ATM ...

What is DNA, and how does it work? You don't need a degree in genetics to understand. Here, we'll give an overview of DNA and ...

When tested in mice, the compound—named BBI-2779—shrank gastric tumors and prevented the cancer from developing resistance to ...