Researchers at the Center for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy ...

The study helps partly explain why: the metabolic enzyme IMPDH2 relocates to the nucleus of TNBC cells to assist in DNA repair processes. "IMPDH2 acts like a mechanic in the cell's nucleus, ...

Metabolic enzymes, typically associated with energy production, are now discovered to also play essential roles in the nucleus, such as orchestrating cell division and DNA repair. This breakthrough, ...

College of Medicine and Imperial College London explored how nerve cells repair themselves, which could lead to new ...

Studies suggest the cell is more interconnected than previously thought, opening up "exciting possibilities for science and medicine." ...

The award will fund work on DNA replication and pathways for cancer treatment, and create a community lab for local students to get research experience.

MSI cancer cells, which have a defect in DNA repair, become dependent on WRN for survival. When WRN is inhibited, these cells cannot repair DNA damage, leading to their death, while healthy cells ...