It's been a rugged season for coach Ryan Walters and the Purdue Boilermakers. They endured the most lopsided loss in school history, 66-7, haven't won a game since August and still don't have a victory over an FBS team.

Penn State by 28 1/2. Series record: Penn State leads 16-3-1. The Nittany Lions are one of four teams still contending to reach the Big Ten title game. But those faint hopes almost certainly would vanish with another loss,

It's Purdue vs Ohio State in Week 11 of the 2024 college football season. Follow along for live score and game updates at Ohio Stadium.

No one needs to remind coach Ryan Day what's at stake for No. 2 Ohio State. The Buckeyes probably have to win their remaining games to keep their national championship hopes alive, and they sure can't afford a letdown against Northwestern at Wrigley Field on Saturday.

It's Ohio State vs Northwestern in Week 12 of the 2024 college football season. Who wins? See predictions and picks, plus the odds for the game.