San Francisco 49ers safety Talanoa Hufanga is poised to make his season debut on Sunday against the Los Angeles Rams.

The injury bug has bitten the San Francisco 49ers. First, it was RB Christian McCaffrey and rookie WR Ricky Pearsall. That ...

San Francisco 49ers linebackers Demetrius Flannigan-Fowles and Curtis Robinson joined the 49ers "You've Got Mail" podcast ...

George Kittle is doubtful for Sunday's game at Los Angeles with a hamstring injury, while two of San Francisco's top ...

There may not be two teams more injured than the Los Angeles Rams and San Francisco 49ers, which will have a big impact on ...

Kyle Shanahan told NBC Sports Bay Area's Greg Papa on "49ers Game Plan" that Fred Warner is having the best season of his ...

As the San Francisco 49ers gear up for a crucial Week 3 showdown against the Los Angeles Rams, they are facing some ...

The San Francisco 49ers will likely be without All-Pro tight end George Kittle for Sunday's game against the Los Angeles Rams ...

George Kittle, Deebo Samuel, and Christian McCaffrey have all scored multiple touchdowns in the 49ers’ recent visits to SoFi Stadium.

San Francisco 49ers star tight end George Kittle is doubtful for Sunday's game at the Los Angeles Rams due to a hamstring ...

Check out some of S Talanoa Hufanga's must-visit spots around Los Angeles, California ahead of the 49ers vs. Rams Week 3 ...

George Kittle is doubtful for Sunday's game at Los Angeles with a hamstring injury, while two of San Francisco's top ...